Early Cities Spurred Evolution of Immune System? [ "Amazing" DNA results show benefits ]

As in cities today, the earliest towns helped expose their inhabitants to inordinate opportunities for infection -- and today their descendants are stronger for it, a new study says. "If cities increase the amount of disease people are exposed to, shouldn't they also, over time, make them natural places for disease resistance to evolve?" asked study co-author Mark Thomas, a biologist at University College London... study co-author Ian Barnes, a molecular paleobiologist at University College London, screened DNA samples from 17 groups long associated with particular regions of Europe, Asia, and Africa -- for example Anatolian Turks and the southern...

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Immune system of healthy adults may be better prepared than expected to fight 2009 H1N1 influenza

WHAT: A new study shows that molecular similarities exist between the 2009 H1N1 influenza virus and other strains of seasonal H1N1 virus that have been circulating in the population since 1988. These results suggest that healthy adults may have a level of protective immune memory that can blunt the severity of infection caused by the 2009 H1N1 influenza virus. The study team was led by Bjoern Peters, Ph.D., and Alessandro Sette, Ph.D., of La Jolla Institute for Allergy and Immunology, Calif., grantees of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The...

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Computer Simulation Sheds Light on Body's Immune Response to Flu

Rochester, NY (OBBeC) - Researchers have reported new revelations on how the body responds to flu. According to the report, scientists at the University of Rochester Medical Center have for the first time -- with the use of a computer simulation -- successfully tested a major portion of the body's immune reaction to influenza type A, with implications for treatment design and preparation ahead of future pandemics. The work has been accepted for publication, and posted online, by the Journal of Virology. The new "global" flu model is built out of preexisting, smaller-scale models that capture in mathematical equations millions...

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Broccoli May Help Boost Aging Immune System

Broccoli May Help Boost Aging Immune SystemBroccoli. (Credit: Image courtesy of University of California - Los Angeles)ScienceDaily (Mar. 10, 2008) — Eat your broccoli! That's the advice from UCLA researchers who have found that a chemical in broccoli and other cruciferous vegetables may hold a key to restoring the body's immunity, which declines as we age. Published in the online edition of the Journal of Allergy and Clinical Immunology, the study findings show that sulforaphane, a chemical in broccoli, switches on a set of antioxidant genes and enzymes in specific immune cells, which then combat the injurious effects of molecules...

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Strange Creature Immune to Pain (Naked mole rats)

As vulnerable as naked mole rats seem, researchers now find the hairless, bucktoothed rodents are invulnerable to the pain of acid and the sting of chili peppers. A better understanding of pain resistance in these sausage-like creatures could lead to new drugs for people with chronic pain, scientists added. Naked mole rats live in cramped, oxygen-starved burrows some six feet underground in central East Africa. Unusually, they are cold-blooded — which, as far as anyone knows, is unique among mammals. "They're the nicest, sweetest animals I've ever worked with — they look frightening, but they're very gentle," said neurobiologist Thomas...

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Potato Salad May Help the Immune System

Source: Society of Chemical Industry Date: June 25, 2007 Potato Salad May Help the Immune System Science Daily — It has long been known that eating potatoes is good for bowel health, but new research suggests that they may also have a beneficial effect on the whole immune system. Especially if eaten cold or in a potato salad, Anne Pichon reports in Chemistry & Industry. Spanish researchers found that growing pigs fed large quantities of raw potato starch (RPS) had a healthier bowel. Not a surprise, but they also found that RPS pigs had decreased levels of white blood cells,...

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Create A Back-Up Copy Of Your Immune System

Create a back-up copy of your immune system 22 June 2007 NewScientist.com news service Andy Coghlan Imagine having a spare copy of your immune system on ice, ready to replace your existing one should you fall victim to AIDS, an autoimmune disease, or have to undergo extensive chemotherapy for cancer. An Anglo-American company called Lifeforce has received permission from the US Food and Drug Administration to do just that. The firm collects 480-millilitre samples of blood from healthy individuals, extracts the white blood cells and stores them as an insurance policy against future disease. The service comes at a price,...

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'Rebuilt' immune system shakes off diabetes

Diabetics appear to have been cured with a one-off treatment that rebuilds their immune system, according to a new study. The technique, which uses patients' own bone marrow cells, has freed 14 of 15 patients with type 1 diabetes from their dependence on insulin medication. So far, participants in the trial have gone 18 months without insulin therapy following the procedure, on average. One patient has lasted three years without needing such injections. In patients with type 1 diabetes, which typically strikes in early childhood or adolescence, the immune system appears to erroneously attack cells in the pancreas that produce...

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Are Some People Immune To Avian Flu?

Source: Public Library of Science Date: February 28, 2007 Are Some People Immune To Avian Flu? Science Daily — New results from Richard Webby at St. Jude Children's Research Hospital and colleagues published in the international open-access medical journal PLoS Medicine suggest that the answer might be yes. Neuraminidase ribbon diagram. (Image courtesy of PLoS Medicine)The H5N1 avian flu virus is quite different from the seasonal H1N1 and H3N2 flu viruses most humans have been exposed to, which is why many scientists believe that H5N1 could start a new pandemic. (The H and N refer to two virus components, the...

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The Antibiotic Vitamin

The Antibiotic VitaminDeficiency in vitamin D may predispose people to infection Janet Raloff In April 2005, a virulent strain of influenza hit a maximum-security forensic psychiatric hospital for men that's midway between San Francisco and Los Angeles. John J. Cannell, a psychiatrist there, observed with increasing curiosity as one infected ward after another was quarantined to limit the outbreak. Although 10 percent of the facility's 1,200 patients ultimately developed the flu's fever and debilitating muscle aches, none did in the ward that he supervised. WINTER WOES. Cold-weather wear and the sun's angle in the winter sky limit how much ultraviolet...

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