Getting a Lungful of Stem Cells

Treating lung diseases is a high priority--chronic lung diseases are the fourth leading cause of death in the U.S. Now a Canadian team has successfully treated a rare, progressive lung disease, pulmonary hypertension, using the patient's own genetically-modified adult stem cells.   The company Osiris has also started a Phase II clinical trial using its adult stem cell product, Prochymal, for moderate to severe chronic obstructive lung disease. Researchers at Vermont College of Medicine have also shown that cord blood stem cells has the potential to regenerate lung tissue.

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Good News: Adult Stem Cells Treat Lung Disease

Two Canadians have been injected with a genetically modified version of their own adult stem cells in an attempt to cure pulmonary hypertension, a rare, debilitating lung disease. The procedure, which has successfully cured rats with pulmonary hypertension, has halted the progress of the disease in the patients. The first patient, who has had the disease for 13 years, is reporting no ill effects from the treatment and has seen her condition improve. Researchers are hopeful that the treatment eventually will reverse or even cure the disease. "The use of ethical stem cells to treat disease is a positive and...

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Viagra may be useful for serious lung disease

NEW YORK (Reuters Health) - Treatment with Viagra (sildenafil) can improve exercise capacity and functional ability in patients with pulmonary arterial hypertension, a serious disease involving high pressure in the blood vessels that enter the lungs, new research suggests. The findings, which appear in The New England Journal of Medicine, are based on a study of 278 patients who were randomly selected to receive Viagra, at one of three doses, or inactive "placebo" three times daily for 12 weeks. The main endpoint was the distance walked in 6 minutes. According to the report, the study did not have enough patients...

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