Dihydrofolate reductase
Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.
Dihydrofolate reductaseDihydrofolate reductase inhibitorDihydrofolic acidIclaprimTrimethoprimEnzymePyrimethamineFolic acidCycloguanilTrimetrexateAminopterinFolate deficiencyEnzyme kineticsHAT mediumTetrahydrofolic acidDihydrobiopterinDiaminopyrimidineBrodimoprimAntifolateDihydropteroate
Ribonucleotide reductasePemetrexedTrimethoprim/sulfamethoxazoleBruce DonaldProguanilREPIN1TetroxoprimMdm2TetrahydrobiopterinPrimidoneAntimalarial medicationLong non-coding RNAPteridine reductaseList of enzymesList of EC numbers (EC 1)Sulfonamide (medicine)Purine metabolismE2FHit selectionMir-24 microRNA precursor family
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