Phosphodiesterase inhibitor
A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).
Phosphodiesterase inhibitorPhosphodiesterase-4 inhibitorSildenafilPDE5 inhibitorTheophyllineCaffeineAcetildenafilMoxaverineRolipramIbudilastCyclic guanosine monophosphatePDE3 inhibitorPhosphodiesteraseZaprinastIBMXEtazolateList of MeSH codes (D16)PDE3CGMP-specific phosphodiesterase type 5PDE5 drug design
Dyphylline8-Cyclopentyl-1,3-dimethylxanthineCartazolateEnprofyllineManagement of heart failureATC code C01VasodilationDilated cardiomyopathyC10H14N4O2RPL-554EnoximoneEHNAPhosphodiesterase 2Discovery and development of dual serotonin and norepinephrine reuptake inhibitorsAmrinoneBRL-50481DipropylcyclopentylxanthineSomatomedin BEpimediumEnzyme inhibitor
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